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Index > Protein center > GHR(Gene name) > Chicken
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  • GHR (Gene name),
  • Growth hormone receptor (Protein name ),  GHR_CHICK from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    GHR;
    Protein name:
    Growth hormone receptor(GH receptor);
    Alternative:
    Somatotropin receptor;
    Organism:
    Chicken (Gallus gallus). 
    General Annotation
    Sub Unit:
    On growth hormone (GH) binding, forms homodimers and binds JAK2 via a box 1-containing domain (By similarity). Binding to SOCS3 inhibits JAK2 activation, binding to CIS and SOCS2 inhibits STAT5 activation.
    Function:
    The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway.
    Protein Attributes:
    Sequence length:
    608
    Sequence:
    50:
    MDLRHLLFTL | ALVCANDSLS | ASDDLLQWPQ | ISKCRSPELE | TFSCYWTDGK | 
    100:
    VTTSGTIQLL | YMKRSDEDWK | ECPDYITAGE | NSCYFNTSYT | SIWIPYCVKL | 
    150:
    ANKDEVFDEK | CFSVDEIVLP | DPPVHLNWTL | LNTSQTGIHG | DIQVRWDPPP | 
    200:
    TADVQKGWIT | LEYELQYKEV | NETKWKELEP | RLSTVVPLYS | LKMGRDYEIR | 
    250:
    VRSRQRTSEK | FGEFSEILYV | SFTQAGIEFV | HCAEEIEFPW | FLVVVFGVCG | 
    300:
    LAVTAILILL | SKQPRLKMLI | FPPVPVPKIK | GIDPDLLKKG | KLDEVNSILA | 
    350:
    SHDNYKTQLY | NDDLWVEFIE | LDIDDSDEKN | RVSDTDRLLS | DDHLKSHSCL | 
    400:
    GAKDDDSGRA | SCYEPDIPET | DFSASDTCDA | ISDIDQFKKV | TEKEEDLLCL | 
    450:
    HRKDDVEALQ | SLANTDTQQP | HTSTQSESRE | SWPPFADSTD | SANPSVQTQL | 
    500:
    SNQNSLTNTD | FYAQVSDITP | AGSVVLSPGQ | KSKVGRAQCE | SCTEQNFTMD | 
    550:
    NAYFCEADVK | KCIAVISQEE | DEPRVQEQSC | NEDTYFTTES | LTTTGINLGA | 
    600:
    SMAETPSMEM | PVPDYTSIHI | VHSPQGLVLN | ATALPVPEKE | FNMSCGYVST | 
    608:
    DQLNKIMP
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    UniGene:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Chicken GH receptor
    Cat.:
    E1036h
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    96T
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    ELISA Kit for Chicken GH receptor
    Cat.:
    E1036p
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    96T
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    ELISA Kit for Chicken GH receptor
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    E1036m
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    96T
    ELISA Kit for Chicken GH receptor
    Cat.:
    E1036c
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    96T
    ELISA Kit for Chicken GH receptor
    Cat.:
    E1036d
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    96T
    ELISA Kit for Chicken GH receptor
    Cat.:
    E1036r
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    ELISA Kit for Chicken GH receptor
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    ELISA Kit for Chicken GH receptor
    Cat.:
    E1036b
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    Packing:
    96T
    CLIA Kit for Chicken GH receptor
    Cat.:
    U1036d
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    96T
    CLIA Kit for Chicken GH receptor
    Cat.:
    U1036r
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    96T
    CLIA Kit for Chicken GH receptor
    Cat.:
    U1036c
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    96T
    CLIA Kit for Chicken GH receptor
    Cat.:
    U1036p
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Chicken GH receptor
    Cat.:
    U1036m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken GH receptor
    Cat.:
    U1036b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken GH receptor
    Cat.:
    U1036h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Chicken GH receptor
    MSDS:
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    Polyclonal Antibody for Chicken GH receptor
    Cat.:
    P1036Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Chicken GH receptor
    Cat.:
    P1036Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Chicken GH receptor
    Polyclonal Antibody for Chicken GH receptor
    Cat.:
    P1036Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Chicken GH receptor
    Polyclonal Antibody for Chicken GH receptor
    Polyclonal Antibody for Chicken GH receptor
    Polyclonal Antibody for Chicken GH receptor
    Monoclonal Antibody for Chicken GH receptor
    Monoclonal Antibody for Chicken GH receptor
    Monoclonal Antibody for Chicken GH receptor
    Monoclonal Antibody for Chicken GH receptor
    Monoclonal Antibody for Chicken GH receptor
    Monoclonal Antibody for Chicken GH receptor
    Monoclonal Antibody for Chicken GH receptor
    Monoclonal Antibody for Chicken GH receptor
    Protein for Chicken GH receptor
    Cat.:
    R1036h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Chicken GH receptor
    Protein for Chicken GH receptor
    Protein for Chicken GH receptor
    Protein for Chicken GH receptor
    Protein for Chicken GH receptor
    Protein for Chicken GH receptor
    Protein for Chicken GH receptor

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    References
    1. 1.
      "Molecular cloning of the chicken growth hormone receptor complementary deoxyribonucleic acid: mutation of the gene in sex-linked dwarf chickens."
      Burnside J. , Liou S.S. , Cogburn L.A.
      Endocrinology128:3183-3192(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Liver.
    2. 2.
      "Overexpression of a truncated growth hormone receptor in the sex-linked dwarf chicken: evidence for a splice mutation."
      Huang N. , Cogburn L.A. , Agarwal S.K. , Marks H.L. , Burnside J.
      Mol. Endocrinol.7:1391-1398(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-112
      tissue: Liver.
    3. 3.
      "Generation of chicken growth hormone-binding proteins by proteolysis."
      Vleurick L. , Kuhn E.R. , Decuypere E. , Burnside J. , Pezet A. , Edery M.
      Gen. Comp. Endocrinol.113:283-289(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEOLYTIC PROCESSING
    4. 4.
      "Internalization of the chicken growth hormone receptor complex and its effect on biological functions."
      Kuhn E.R. , Vleurick L. , Edery M. , Decuypere E. , Darras V.M.
      Comp. Biochem. Physiol.132B:299-308(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERNALIZATION;JAK2 ACTIVATION
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